Guangzhou is facing the challenges of population aging while facilities are lack of care for the elderly. A growing number of researches have shown that built environments are closely associate with the mental and physical health of the elderly. Neighborhoods’ outdoor environment with different quality in the city will aggravate the social and healthcare unfairness of older adults. It is urgent for the local government and landscape architects to consider how to upgrade the existing outdoor environment for healthy aging. The project responded to these problems through the perspective of mood effect, entrusted by the local government. Based on the local conditions and the mental health needs of the elderly, the project proposed 4 types of typical strategies through field surveys and analysis. The project created 1) a neighborhood of vitality in high-quality neighborhoods; 2) a neighborhood of barrier-free in medium-quality neighborhoods; 3) a neighborhood of commodiousness in poor-quality neighborhoods; 4) assisted living streets. The project also develops a landscape toolkit for mental health improvement to implement the regional vision for the future.